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9 March 2023 Optoacoustic-Ultrasound (OPUS) monitoring of High-Intensity Focused Ultrasound (HIFU)-induced heating and cavitation with a multi-segment transducer array
Çağla Özsoy, Berkan Lafci, Michael Reiss, Xosé Luís Deán-Ben, Daniel Razansky
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Proceedings Volume PC12379, Photons Plus Ultrasound: Imaging and Sensing 2023; PC123791L (2023) https://doi.org/10.1117/12.2649652
Event: SPIE BiOS, 2023, San Francisco, California, United States
Abstract
High-intensity focused ultrasound (HIFU) capitalizes on both heating and cavitation effects for the treatment of several conditions. Optoacoustic (OA) imaging has previously been shown to provide high sensitivity to temperature changes and coagulation in HIFU-ablated tissues. In this work, we demonstrate the feasibility of real-time monitoring of heating and cavitation with a hybrid optoacoustic-ultrasound (OPUS) imaging system based on a multi-segment transducer array. The OPUS results in experiments with liver tissues ex-vivo and a mouse post-mortem were validated with thermal camera measurements and with cryo-sections of the mouse. The suggested approach thus holds promise to be clinically translated.
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Çağla Özsoy, Berkan Lafci, Michael Reiss, Xosé Luís Deán-Ben, and Daniel Razansky "Optoacoustic-Ultrasound (OPUS) monitoring of High-Intensity Focused Ultrasound (HIFU)-induced heating and cavitation with a multi-segment transducer array", Proc. SPIE PC12379, Photons Plus Ultrasound: Imaging and Sensing 2023, PC123791L (9 March 2023); https://doi.org/10.1117/12.2649652
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KEYWORDS
Cavitation
Ultrasonography
Transducers
Liver
Tissues
Optoacoustics
Cancer
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