An automatic image registration algorithm to align serial photoacoustic images: a step toward repeatable longitudinal imaging

Bruno De Santi; Lucia Kim; Rianne Bulthuis; Felix Lucka; Ben Cox; Srirang Manohar

doi:10.1117/12.2650407

27 March 2023 An automatic image registration algorithm to align serial photoacoustic images: a step toward repeatable longitudinal imaging

Bruno De Santi, Lucia Kim, Rianne Bulthuis, Felix Lucka, Ben Cox, Srirang Manohar

Author Affiliations +

Proceedings Volume PC12379, Photons Plus Ultrasound: Imaging and Sensing 2023; PC1237938 (2023) https://doi.org/10.1117/12.2650407
Event: SPIE BiOS, 2023, San Francisco, California, United States

Conference Poster

Abstract

Neoadjuvant chemotherapy (NAC) is a systemic therapy used to treat breast cancer prior to surgery. Multispectral photoacoustic (PA) imaging has been showing promising results in breast cancer. However, in order to use PA imaging in NAC response monitoring registration of the serial PA images is needed. In this study we propose and validate an automatic image registration algorithm to align intra-patient repeated breast PA images that can correct for patient repositioning and local non-rigid tissue deformation. Thanks to this algorithm, PA imaging can prove to be a non-invasive technique capable of monitoring the tumour functionality over time.

Citation Download Citation

Bruno De Santi, Lucia Kim, Rianne Bulthuis, Felix Lucka, Ben Cox, and Srirang Manohar "An automatic image registration algorithm to align serial photoacoustic images: a step toward repeatable longitudinal imaging", Proc. SPIE PC12379, Photons Plus Ultrasound: Imaging and Sensing 2023, PC1237938 (27 March 2023); https://doi.org/10.1117/12.2650407

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