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15 March 2023 Evaluation of light penetration depth for Imaging Mueller polarimeter operating in a visible wavelength range in reflection geometry: ex-vivo studies of healthy brain white matter (Conference Presentation)
Omar Rodríguez-Núñez, Leonard A. Felger, Romain Gross, Theoni Maragkou, Richard McKinley, Stefano Moriconi, Michael Murek, Angelo Pierangelo, Philippe Schucht, Irena Zubak, Tatiana Novikova
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Proceedings Volume PC12382, Polarized Light and Optical Angular Momentum for Biomedical Diagnostics 2023; PC1238209 (2023) https://doi.org/10.1117/12.2650008
Event: SPIE BiOS, 2023, San Francisco, California, United States
Abstract
The identification of the border between tumor and healthy brain tissue remains a main challenge in glioma surgery. To address this problem we suggest using the Mueller Polarimetric Imaging (MPI) operating in the visible spectral range. In our prior studies, we demonstrated the potential of MPI to assess the anisotropy of healthy brain tissue in fixed and fresh specimens. In this study, we use the MPI system in backscattering geometry in order to evaluate and determine the depth of light penetration through the evaluation of 2D surface polarimetric maps of the formalin-fixed human cerebral corpus callosum sections of different thicknesses.
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Omar Rodríguez-Núñez, Leonard A. Felger, Romain Gross, Theoni Maragkou, Richard McKinley, Stefano Moriconi, Michael Murek, Angelo Pierangelo, Philippe Schucht, Irena Zubak, and Tatiana Novikova "Evaluation of light penetration depth for Imaging Mueller polarimeter operating in a visible wavelength range in reflection geometry: ex-vivo studies of healthy brain white matter (Conference Presentation)", Proc. SPIE PC12382, Polarized Light and Optical Angular Momentum for Biomedical Diagnostics 2023, PC1238209 (15 March 2023); https://doi.org/10.1117/12.2650008
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KEYWORDS
Brain
Polarimetry
Neuroimaging
Tumors
Brain mapping
Tissue optics
Anisotropy
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