Quantitative phase imaging to quantify cell growth and response to therapy in space and time (Conference Presentation)

Thomas A. Zangle

doi:10.1117/12.2656156

16 March 2023 Quantitative phase imaging to quantify cell growth and response to therapy in space and time (Conference Presentation)

Thomas A. Zangle

Author Affiliations +

Proceedings Volume PC12389, Quantitative Phase Imaging IX; PC123890S (2023) https://doi.org/10.1117/12.2656156
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

Measuring cancer cell response to therapy is an essential component of developing new therapies or determining the optimal treatment for a particular patient. In this talk I will discuss the use of quantitative phase imaging (QPI) to measure the distribution of mass within single cells, and how this distribution changes over time. Based on this approach, my lab has developed new approaches to quantify the time-dependence and intracellular spatial distribution of cell response to small-molecule inhibitors. These data can be used to study basic cell physiology, as well as how cancer cells respond to therapies.

Conference Presentation

Citation Download Citation

Thomas A. Zangle "Quantitative phase imaging to quantify cell growth and response to therapy in space and time (Conference Presentation)", Proc. SPIE PC12389, Quantitative Phase Imaging IX, PC123890S (16 March 2023); https://doi.org/10.1117/12.2656156

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