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We have successfully designed, fabricated, and demonstrated the use of a planar dielectric metasurface to generate AAF beams for biomedical applications. Our results demonstrate the potential of using metasurface for precise control of the local phase of light and the generation of unique optical properties. The high-intensity contrast between the initial and focal plane was used for fluorescence-guided light treatment of microspheres and mouse cardiac slices. Our ultrathin (800 nm) Nano-photonics metasurface allows for designing miniature integrated optical devices for biomedical instruments. The AAF beam& #39;s high-energy-density hotspot could be useful in Nano-surgery, high-resolution imaging, and photo-dynamic therapy.
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