Non-melanoma skin cancers (NMSC) pose challenges with current clinical approaches. In this context, Multispectral Optoacoustic Tomography (MSOT) offers a promising non-invasive imaging solution. With high isotropic resolution and contrast-enhanced capabilities, MSOT provides a 3D tumor map by resolving melanin and haemoglobin signals. Our feature extraction and automated level-set image segmentation algorithm enables tumor profiling and precise boundary delineation of width, depth, and volume. Validated against histology, these metrics aid preoperative tumor mapping and surgical planning as it fosters a comprehensive understanding of tumor morphology and metabolic activities. Thus, clinicians can optimize NMSC management, revolutionizing diagnostics and treatment for improved patient outcomes.
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