Fluorescence-guided photoimmunotherapy for peritoneal carcinomatosis

Barry Liang; Sumiao Pang; Robert Perttila; Chen-Hua Ma; Payal Srivastava; Brandon Gaitan; Aaron Sorrin; Nada Fadul; Idrisa Rahman; Zoe Ylöniemi; Dana Roque; Tayyaba Hasan; Petteri Uusimaa; Huang-Chiao Huang

doi:10.1117/12.3011885

8 April 2024 Fluorescence-guided photoimmunotherapy for peritoneal carcinomatosis

Barry Liang, Sumiao Pang, Robert Perttila, Chen-Hua Ma, Payal Srivastava, Brandon Gaitan, Aaron Sorrin, Nada Fadul, Idrisa Rahman, Zoe Ylöniemi, Dana Roque, Tayyaba Hasan, Petteri Uusimaa, Huang-Chiao Huang

Author Affiliations +

Proceedings Volume PC12823, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXXII; PC128230D (2024) https://doi.org/10.1117/12.3011885
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

Peritoneal metastasis, incomplete resection, and drug resistance render advanced-stage ovarian cancer virtually incurable with current surgical and chemotherapy approaches. Photoimmunotherapy is increasingly used to treat unresectable metastases, but many innovations are lost in translation due to heterogeneous treatment effects. This study integrates targeted nanotechnology, fluorescence-guided intervention, and a medical laser system to improve the safety, efficacy, and consistency of photoimmunotherapy for peritoneal metastases.

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Citation Download Citation

Barry Liang, Sumiao Pang, Robert Perttila, Chen-Hua Ma, Payal Srivastava, Brandon Gaitan, Aaron Sorrin, Nada Fadul, Idrisa Rahman, Zoe Ylöniemi, Dana Roque, Tayyaba Hasan, Petteri Uusimaa, and Huang-Chiao Huang "Fluorescence-guided photoimmunotherapy for peritoneal carcinomatosis", Proc. SPIE PC12823, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXXII, PC128230D (8 April 2024); https://doi.org/10.1117/12.3011885

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