Optical fiber enables the implementation of flexible medical endoscopes. Here, we present the development of fiber-optic endoscopic ultrasound, which utilizes laser pulse absorption to generate ultrasound waves and a fiber-optic acoustic sensor to detect echo waves. Compared to its piezoelectric counterpart, the fiber-optic sensor has a significantly higher detection sensitivity and broader bandwidth. As a result, we were able to perform in vivo rotational-scanning (or B-mode) imaging of the gastrointestinal tract and extraluminal structures of a rat with an operating frequency of 20 MHz, an imaging depth of 2 cm, and a frame rate of 1 Hz.
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