Photoacoustic-Brillouin multimodal imaging modality

Chenjun Shi; Yan Yan; Mohammad Mehrmohammadi; Jitao Zhang

doi:10.1117/12.3002144

13 March 2024 Photoacoustic-Brillouin multimodal imaging modality

Chenjun Shi, Yan Yan, Mohammad Mehrmohammadi, Jitao Zhang

Proceedings Volume PC12844, Optical Elastography and Tissue Biomechanics XI; PC128440H (2024) https://doi.org/10.1117/12.3002144
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

In this work, we developed a new multimodal technology that can simultaneously measure a subset of mechanical, optical, and acoustical properties of the sample, which is based on the integration of Brillouin and photoacoustic (PA) microscopy. Notably, this integration offers a novel approach to probing the refractive index of the sample, which is inaccessible through each technique alone. As a proof-of-concept, we demonstrated the feasibility of the combined setup to obtain the co-registered Brillouin and time-resolved PA signals in a synthetic phantom made of kerosene and CuSO4 aqueous solution. In addition, we measured the refractive index of saline solutions and validated the result in comparison with previously reported data.

Conference Presentation

Citation Download Citation

Chenjun Shi, Yan Yan, Mohammad Mehrmohammadi, and Jitao Zhang "Photoacoustic-Brillouin multimodal imaging modality", Proc. SPIE PC12844, Optical Elastography and Tissue Biomechanics XI, PC128440H (13 March 2024); https://doi.org/10.1117/12.3002144

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