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Chapter 29:
Quantum-Dot Biosensors using Fluorescence Resonance Energy Transfer (FRET)
Editor(s): Leo Esaki; Klaus von Klitzing; Manijeh Razeghi
Author(s): Garland, James W., Episensors, Inc.; Ramadurai, Dinakar, Episensors, Inc.; Sivananthan, Siva, Sivananthan Laboratories, Inc.,; Arnold, Heather N., Northwestern Univ.; Hersam, Mark C., Northwestern Univ.
This chapter primarily describes a biosensor developed by EPIR Technologies, Inc. (EPIR) that allows multichannel real-time detection of biological agents (antigens) with exceptional specificity and sensitivity. However, this biosensor should be considered only as a prototype proof of concept and as an example of the power of nanobiotechnology. Nanobiotechnology and bionanotechnology are very new fields (the term nanobiotechnology was first used in the year 2000, and the term bionanotechnology was not introduced until 2004). As many readers of this book may have had no previous introduction to the field, this introduction is meant primarily to briefly introduce the reader to the field, hopefully stirring enough interest to motivate the reader to investigate it further.
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