Near-infrared luminescent nanomaterials for in-vivo optical imaging

Peter Bachmann; Helga Hummel; Thomas Jüstel; Jacqueline Merikhi; Cornelis R. Ronda; Volker Weiler

doi:10.1117/1.3039801

1 November 2008 Near-infrared luminescent nanomaterials for in-vivo optical imaging

Peter Bachmann, Helga Hummel, Thomas Jüstel, Jacqueline Merikhi, Cornelis R. Ronda, Volker Weiler

Author Affiliations +

Journal of Nanophotonics, Vol. 2, Issue 1, 021920 (November 2008). https://doi.org/10.1117/1.3039801

Abstract

Optical imaging using unspecific contrast agents as well as targeted and disease-specific agents play a vital role in preclinical research. Moreover, optical imaging is on the verge of establishing itself as a clinically relevant imaging modality. Also in-vitro diagnostical procedures rely to a large degree on optical labels to report disease-specific events. Materials that fulfill the basic requirements of this market are being used today, with cyanine dyes and semiconductor quantum dots being excellent examples. Other materials are being tested in laboratories throughout the world. Design rules suitable to develop new optical labels for in-vivo near-infrared optical imaging procedures have been formulated by us, and we have developed synthesis routes that lead to nano particles with small diameter, narrow size distribution, high quantum yield, and with stable surfaces required for bioconjugation to disease-specific ligands.

Citation Download Citation

Peter Bachmann, Helga Hummel, Thomas Jüstel, Jacqueline Merikhi, Cornelis R. Ronda, and Volker Weiler "Near-infrared luminescent nanomaterials for in-vivo optical imaging," Journal of Nanophotonics 2(1), 021920 (1 November 2008). https://doi.org/10.1117/1.3039801

Published: 1 November 2008

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available