Due to the lack of support for a high-resolution image in a short time, land cover change detection is always applied on the multitemporal remote-sensed images with different resolutions. The coarse-resolution image contains a large number of mixed pixels, which can seriously limit the utility of the change detection. Soft classification (SC) can be applied to improve this situation through deriving the abundances and generating the fractional change map, but it cannot provide the spatial distribution of the subpixels. Subpixel mapping (SPM) is a potential solution to resolve this problem, and is designed to use the proportions to obtain a sharpened thematic map at a subpixel scale. Based on this thought, the subpixel scale land cover change mapping result can be realized by integrating these two key techniques. However, in practice, there is a serious limitation to the detail and accuracy of the result, because when the scale factor between the different resolution images is large, the subpixel configuration is complex and the data volumes will be amplified. Moreover, with the high proportion of the changed area in the whole image, the change detection process at the subpixel level gets more difficult. The SPM technique is generally performed based only on the abundances of each and the spatial dependence assumption, so it cannot satisfy the demand. In order to overcome this shortcoming, several new reasonable subpixel scale change detection rules are defined in this paper, which dictate the land cover change map must be constructed according to the existing high-resolution image. The output from SC and prior information of the subpixel feature arrangement is applied into a modified cellular automata (CA) model, which can be regarded as a more reasonable tool to monitor the subpixel changes to resolve the big-data problem. Two experiments are performed and the results prove that the proposed method can effectively improve the accuracy of the change detection maps of the spatial distribution in a subpixel scale.