1 November 2005 Erythrocyte structure and dynamics quantified by Hilbert phase microscopy
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J. of Biomedical Optics, 10(6), 060503 (2005). doi:10.1117/1.2149847
Abstract
We present a new quantitative method for investigating red blood cell morphology and dynamics. The instrument integrates quantitative phase microscopy with an inverted microscope, which makes it particularly suitable for the noninvasive assessment of live erythrocytes. In particular, we demonstrate the ability of this approach to quantify noninvasively cell volume and dynamic morphology. The subnanometer path-length sensitivity at the millisecond time scales is exemplified by measuring the hemoglobin flow out of the cell during hemolysis.
Gabriel Popescu, Takahiro Ikeda, Catherine Best, Kamran Badizadegan, Ramachandra R. Dasari, Michael S. Feld, "Erythrocyte structure and dynamics quantified by Hilbert phase microscopy," Journal of Biomedical Optics 10(6), 060503 (1 November 2005). http://dx.doi.org/10.1117/1.2149847
Submission: Received ; Accepted
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KEYWORDS
Microscopy

High power microwaves

Blood

Microscopes

Refractive index

Phase measurement

Photonics

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