1 March 2005 Diffraction-free acoustic detection for optoacoustic depth profiling of tissue using an optically transparent polyvinylidene fluoride pressure transducer operated in backward and forward mode
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J. of Biomedical Optics, 10(2), 024035 (2005). doi:10.1117/1.1891443
Abstract
An optoacoustic detection method suitable for depth profiling of optical absorption of layered or continuously varying tissue structures is presented. Detection of thermoelastically induced pressure transients allows reconstruction of optical properties of the sample to a depth of several millimeters with a spatial resolution of 24 µm. Acoustic detection is performed using a specially designed piezoelectric transducer, which is transparent for optical radiation. Thus, ultrasonic signals can be recorded at the same position the tissue is illuminated. Because the optoacoustical sound source is placed in the pulsed-acoustic near field of the pressure sensor, signal distortions commonly associated with acoustical diffraction are eliminated. Therefore, the acoustic signals mimic exactly the depth profile of the absorbed energy. This is illustrated by imaging the absorption profile of a two-layered sample with different absorption coefficients, and of a dye distribution while diffusing into a gelatin phantom.
Michael Jaeger, Joel Niederhauser, Marjaneh Hejazi, Martin Frenz, "Diffraction-free acoustic detection for optoacoustic depth profiling of tissue using an optically transparent polyvinylidene fluoride pressure transducer operated in backward and forward mode," Journal of Biomedical Optics 10(2), 024035 (1 March 2005). http://dx.doi.org/10.1117/1.1891443
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KEYWORDS
Acoustics

Sensors

Absorption

Signal detection

Tissue optics

Transducers

Diffusion

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