1 September 2005 Enhancement of hidden structures of early skin fibrosis using polarization degree patterns and Pearson correlation analysis
Author Affiliations +
J. of Biomedical Optics, 10(5), 051706 (2005). doi:10.1117/1.2073727
Abstract
The skin of athymic nude mice is irradiated with a single dose of x-ray irradiation that initiated fibrosis. Digital photographs of the irradiated mice are taken by illuminating the mouse skin with linearly polarized probe light of 650 nm. The specific pattern of the surface distribution of the degree of polarization enables the detection of initial skin fibrosis structures that were not visually apparent. Data processing of the raw spatial distributions of the degree of polarization based on Fourier filtering of the high-frequency noise improves subjective perception of the revealed structure in the images. In addition, Pearson correlation analysis provides information about skin structural size and directionality.
Alexander P. Sviridov, Victor V. Chernomordik, Moinuddin Hassan, Albert Claude Boccara, Angelo Russo, Paul D. Smith, Amir H. Gandjbakhche, "Enhancement of hidden structures of early skin fibrosis using polarization degree patterns and Pearson correlation analysis," Journal of Biomedical Optics 10(5), 051706 (1 September 2005). http://dx.doi.org/10.1117/1.2073727
JOURNAL ARTICLE
6 PAGES


SHARE
KEYWORDS
Polarization

Skin

Tissue optics

Visualization

X-rays

Cameras

Digital photography

Back to Top