Measurement of burn depths in rats using multiwavelength photoacoustic depth profiling

Mutsuo Yamazaki; Shunichi Sato; Hiroshi Ashida; Daizo Saito; Yoshiaki Okada; Minoru Obara

doi:10.1117/1.2137287

1 November 2005 Measurement of burn depths in rats using multiwavelength photoacoustic depth profiling

Mutsuo Yamazaki; Shunichi Sato; Hiroshi Ashida; Daizo Saito; Yoshiaki Okada; Minoru Obara

Author Affiliations +

J. of Biomedical Optics, 10(6), 064011 (2005). https://doi.org/10.1117/1.2137287

Abstract

We perform measurement of photoacoustic (PA) signals for burned skin in rats in the spectral range of 500 to 650 nm. The wavelength dependence of PA signal amplitude shows characteristics similar to those of the absorption spectrum of hemoglobin, suggesting that the PA signal originates from blood in the uninjured skin tissue under the injured tissue layer. High-contrast signals are obtained in the spectral range of 532 to 580 nm. At 550 nm, a PA detector is scanned on the wounds and PA tomograms are obtained. The tomograms clearly show the zones of stasis, demonstrating that a 2-D PA measurement is useful for burn depth assessment.

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Mutsuo Yamazaki, Mutsuo Yamazaki, Shunichi Sato, Shunichi Sato, Hiroshi Ashida, Hiroshi Ashida, Daizo Saito, Daizo Saito, Yoshiaki Okada, Yoshiaki Okada, Minoru Obara, Minoru Obara, } "Measurement of burn depths in rats using multiwavelength photoacoustic depth profiling," Journal of Biomedical Optics 10(6), 064011 (1 November 2005). https://doi.org/10.1117/1.2137287 . Submission:

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