1 May 2006 Photothermally induced delayed tissue death
Author Affiliations +
J. of Biomedical Optics, 11(3), 030504 (2006). doi:10.1117/1.2210948
Abstract
We report pronounced delayed tissue death in photothermal surgery performed on the livers of live healthy rats with highly concentrated sunlight (ultrabright noncoherent light). Exposure times and power levels were selected to produce immediate necroses of the order of hundreds of cubic millimeters. Pathology reveals that lesion volumes increase by up to a factor of 5 within approximately 24 h after surgery, and then stabilize. Islands of viable cells can persist within damaged tissue, in the immediate vicinity of blood vessels, but also necrose within about 48 h.
Jeffrey M. Gordon, Ruthy Shaco-Levy, Daniel Feuermann, Mahmoud M. Huleihil, Solly Mizrahi, "Photothermally induced delayed tissue death," Journal of Biomedical Optics 11(3), 030504 (1 May 2006). http://dx.doi.org/10.1117/1.2210948
Submission: Received ; Accepted
JOURNAL ARTICLE
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KEYWORDS
Surgery

Tissue optics

Tissues

Liver

Pathology

Blood vessels

Laser therapeutics

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