1 January 2007 Photoacoustic imaging of the microvasculature with a high-frequency ultrasound array transducer
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J. of Biomedical Optics, 12(1), 010501 (2007). doi:10.1117/1.2709850
Abstract
Visualization of microvascular networks could provide new information about function and disease. We demonstrate the capabilities of a 30-MHz ultrasound array system for photoacoustic microscopy of small (≤300 μm) vessels in a rat. 3D images obtained by translating the array in the elevation direction are compared with photographs of excised skin. The system is shown to have 100-μm lateral resolution, 25-μm axial resolution, and 3-mm imaging depth. To our knowledge this is the first report on photoacoustic microscopy of the microvasculature with a high-frequency array transducer. It is anticipated that the system can be used for studying and diagnosing a number of diseases including cancer, atherosclerosis, dermatological disorders, and peripheral microvascular complications in diabetes.
Roger J. Zemp, Rachel Bitton, K. Kirk Shung, Meng-Lin Li, George Stoica, Lihong V. Wang, "Photoacoustic imaging of the microvasculature with a high-frequency ultrasound array transducer," Journal of Biomedical Optics 12(1), 010501 (1 January 2007). http://dx.doi.org/10.1117/1.2709850
Submission: Received ; Accepted
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KEYWORDS
Ultrasonography

Photoacoustic imaging

Transducers

Skin

Data acquisition

Photoacoustic microscopy

Optical fibers

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