1 January 2007 Determination of the optical properties of anisotropic biological media using an isotropic diffusion model
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Abstract
We investigate anisotropic light propagation in biological tissue in steady-state and time domains. Monte Carlo simulations performed for tissue that consists of aligned cylindrical and spherical scatterers show that steady-state and time-resolved reflectance depends strongly on the measurement direction relative to the alignment of the cylinder axis. We examine the determination of optical properties using an isotropic diffusion model and find that in the time domain, in contrast to steady-state spatially resolved reflectance measurements, the obtained absorption coefficient does not depend on the measurement direction and is close to the true value. Contrarily, the derived reduced scattering coefficient depends strongly on the measurement direction in both domains. Measurements of the steady-state and time-resolved reflectance from bovine tendon confirm the theoretical findings.
© (2007) Society of Photo-Optical Instrumentation Engineers (SPIE)
Alwin Kienle, Corinna Wetzel, Andrea Li Bassi, Daniela Comelli, Paola Taroni, Antonio Pifferi, "Determination of the optical properties of anisotropic biological media using an isotropic diffusion model," Journal of Biomedical Optics 12(1), 014026 (1 January 2007). https://doi.org/10.1117/1.2709864 . Submission:
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