1 May 2007 Novel flexible light diffuser and irradiation properties for photodynamic therapy
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J. of Biomedical Optics, 12(3), 034024 (2007). doi:10.1117/1.2749737
Abstract
Many current light diffusers for photodynamic therapy are inflexible, and the applied light dose is difficult to adjust during treatment, especially on complex body surfaces. A thin and flexible luminous textile is developed using plastic optical fibers as a light distributor. The textile diffuser is evaluated for flexibility, irradiance, brightness distribution, and temperature rise with a 652-nm laser set to 100 mW. The bending force of the textile diffuser resembles a defined optical film. On the textile surface, an average output power of 3.6±0.6 mW/cm2 is measured, corresponding to a transmission rate of 40±3.8% on an area of 11 cm2. Aluminum backing enhances the irradiance to the face (treatment side). The measured brightness distribution seems to lie within a range similar to other photodynamic therapy (PDT) devices. A power setting of 100 mW increases the temperature of the textile diffuser surface of up to 27°C, and 1 W raises the temperature above 40°C. Results confirm that the flexible textile diffuser supplies suitable radiation for low fluence rate photodynamic therapy on an area of several cm2.
Bärbel Selm, Markus Rothmaier, Martin Camenzind, Tania N. Khan, Heinrich Walt, "Novel flexible light diffuser and irradiation properties for photodynamic therapy," Journal of Biomedical Optics 12(3), 034024 (1 May 2007). http://dx.doi.org/10.1117/1.2749737
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KEYWORDS
Diffusers

Photodynamic therapy

Phase only filters

Temperature metrology

Aluminum

Optical fibers

Distribution

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