1 May 2007 Novel flexible light diffuser and irradiation properties for photodynamic therapy
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Abstract
Many current light diffusers for photodynamic therapy are inflexible, and the applied light dose is difficult to adjust during treatment, especially on complex body surfaces. A thin and flexible luminous textile is developed using plastic optical fibers as a light distributor. The textile diffuser is evaluated for flexibility, irradiance, brightness distribution, and temperature rise with a 652-nm laser set to 100 mW. The bending force of the textile diffuser resembles a defined optical film. On the textile surface, an average output power of 3.6±0.6 mW/cm2 is measured, corresponding to a transmission rate of 40±3.8% on an area of 11 cm2. Aluminum backing enhances the irradiance to the face (treatment side). The measured brightness distribution seems to lie within a range similar to other photodynamic therapy (PDT) devices. A power setting of 100 mW increases the temperature of the textile diffuser surface of up to 27°C, and 1 W raises the temperature above 40°C. Results confirm that the flexible textile diffuser supplies suitable radiation for low fluence rate photodynamic therapy on an area of several cm2.
© (2007) Society of Photo-Optical Instrumentation Engineers (SPIE)
Bärbel Selm, Bärbel Selm, Markus Rothmaier, Markus Rothmaier, Martin Camenzind, Martin Camenzind, Tania N. Khan, Tania N. Khan, Heinrich Walt, Heinrich Walt, } "Novel flexible light diffuser and irradiation properties for photodynamic therapy," Journal of Biomedical Optics 12(3), 034024 (1 May 2007). https://doi.org/10.1117/1.2749737 . Submission:
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