1 July 2007 Analysis of posterior retinal layers in spectral optical coherence tomography images of the normal retina and retinal pathologies
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J. of Biomedical Optics, 12(4), 041207 (2007). doi:10.1117/1.2771569
Abstract
We present a computationally efficient, semiautomated method for analysis of posterior retinal layers in three-dimensional (3-D) images obtained by spectral optical coherence tomography (SOCT). The method consists of two steps: segmentation of posterior retinal layers and analysis of their thickness and distance from an outer retinal contour (ORC), which is introduced to approximate the normal position of external interface of the healthy retinal pigment epithelium (RPE). The algorithm is shown to effectively segment posterior retina by classifying every pixel in the SOCT tomogram using the similarity of its surroundings to a reference set of model pixels from user-selected area(s). Operator intervention is required to assess the quality of segmentation. Thickness and distance maps from the segmented layers and their analysis are presented for healthy and pathological retinas.
Maciej Szkulmowski, Maciej Wojtkowski, Bartosz Sikorski, Tomasz Bajraszewski, Vivek Jay Srinivasan, Anna Szkulmowska, Jakub J. Kaluzny, James G. Fujimoto, Andrzej Kowalczyk, "Analysis of posterior retinal layers in spectral optical coherence tomography images of the normal retina and retinal pathologies," Journal of Biomedical Optics 12(4), 041207 (1 July 2007). http://dx.doi.org/10.1117/1.2771569
JOURNAL ARTICLE
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KEYWORDS
Image segmentation

Optical coherence tomography

Retina

Eye

Biological research

Pathology

Reflectivity

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