1 July 2007 Three-dimensional optical coherence tomography at 1050 nm versus 800 nm in retinal pathologies: enhanced performance and choroidal penetration in cataract patients
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Abstract
Frequency domain optical coherence tomography (FD-OCT), based on an all-reflective high-speed InGaAs spectrometer, operating in the 1050 nm wavelength region for retinal diagnostics, enables high-speed, volumetric imaging of retinal pathologies with greater penetration into choroidal tissue is compared to conventional 800 nm three-dimensional (3-D) ophthalmic FD-OCT systems. Furthermore, the lower scattering at this wavelength significantly improves imaging performance in cataract patients, thereby widening the clinical applicability of ophthalmic OCT. The clinical performance of two spectrometer-based ophthalmic 3-D OCT systems compared in respect to their clinical performance, one operating at 800 nm with 150 nm bandwidth (~3 μm effective axial resolution) and the other at 1050 nm with 70 nm bandwidth (~7 μm effective axial resolution). Results achieved with 3-D OCT at 1050 nm reveal, for the first time, decisive improvements in image quality for patients with retinal pathologies and clinically significant cataract.
© (2007) Society of Photo-Optical Instrumentation Engineers (SPIE)
Boris Povazay, Boris Povazay, Boris M. Hermann, Boris M. Hermann, Angelika Unterhuber, Angelika Unterhuber, Bernd Hofer, Bernd Hofer, Harald Sattmann, Harald Sattmann, Florian Zeiler, Florian Zeiler, James E. Morgan, James E. Morgan, Christiane Falkner-Radler, Christiane Falkner-Radler, Carl Glittenberg, Carl Glittenberg, Susanne Binder, Susanne Binder, Wolfgang Drexler, Wolfgang Drexler, } "Three-dimensional optical coherence tomography at 1050 nm versus 800 nm in retinal pathologies: enhanced performance and choroidal penetration in cataract patients," Journal of Biomedical Optics 12(4), 041211 (1 July 2007). https://doi.org/10.1117/1.2773728 . Submission:
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