Open Access
1 January 2008 In vivo confocal and multiphoton microendoscopy
Pilhan Kim, Mehron Pouris'haag, Daniel Cote, Charles P. Lin, Seok-Hyun Yun
Author Affiliations +
Abstract
The ability to conduct high-resolution fluorescence imaging in internal organs of small animal models in situ and over time can make a significant impact in biomedical research. Toward this goal, we developed a real-time confocal and multiphoton endoscopic imaging system. Using 1-mm-diameter endoscopes based on gradient index lenses, we demonstrate video-rate multicolor multimodal imaging with cellular resolution in live mice.
©(2008) Society of Photo-Optical Instrumentation Engineers (SPIE)
Pilhan Kim, Mehron Pouris'haag, Daniel Cote, Charles P. Lin, and Seok-Hyun Yun "In vivo confocal and multiphoton microendoscopy," Journal of Biomedical Optics 13(1), 010501 (1 January 2008). https://doi.org/10.1117/1.2839043
Published: 1 January 2008
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CITATIONS
Cited by 123 scholarly publications and 2 patents.
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KEYWORDS
Confocal microscopy

Luminescence

Endoscopes

In vivo imaging

GRIN lenses

Image resolution

Imaging systems

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