1 March 2008 Characteristics of the human isoplanatic patch and implications for adaptive optics retinal imaging
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J. of Biomedical Optics, 13(2), 024008 (2008). doi:10.1117/1.2907211
Conventional adaptive optics enables correction of high-order aberrations of the eye, but only for a single retinal point. When imaging extended regions of the retina, aberrations increase away from this point and degrade image quality. The zone over which aberrations do not change significantly is called the "isoplanatic patch." Literature concerning the human isoplanatic patch is incomplete. We determine foveal isoplanatic patch characteristics by performing Hartmann-Shack aberrometry in 1 deg increments in 8 directions on 7 human eyes. Using these measurements, we establish the correction quality required to yield at least 80% of the potential patch size for a given eye. Single-point correction systems (conventional adaptive optics) and multiple-point correction systems (multiconjugate adaptive optics) are simulated. Results are compared to a model eye. Using the Maréchal criterion for 555-nm light, average isoplanatic patch diameter for our subjects is 0.80±0.10 deg. The required order of aberration correction depends on desired image quality over the patch. For the more realistically achievable criterion of 0.1 μm root mean square (rms) wavefront error over a 6.0-mm pupil, correction to at least sixth order is recommended for all adaptive optics systems. The most important aberrations to target for a multiconjugate correction are defocus, astigmatism, and coma.
Phillip Bedggood, Mary Daaboul, Ross A. Ashman, George G. Smith, Andrew Metha, "Characteristics of the human isoplanatic patch and implications for adaptive optics retinal imaging," Journal of Biomedical Optics 13(2), 024008 (1 March 2008). http://dx.doi.org/10.1117/1.2907211

Adaptive optics



Eye models

Image quality

Monochromatic aberrations

Data modeling

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