1 September 2008 In vivo quantification of gingival inflammation using spectral imaging
Author Affiliations +
J. of Biomedical Optics, 13(5), 054045 (2008). doi:10.1117/1.2982536
Erythema is a reaction of the skin and oral soft tissues commonly associated with inflammation and an increase in blood flow. Diffuse reflection spectroscopy is a powerful tool for the assessment of skin inflammation where erythema has been linked to the relative concentration of oxygenated hemoglobin and blood perfusion. Here we demonstrate the applicability of a spectral imaging method for the quantification of gingival inflammation by looking at the gingival margin and papillary tip erythema. We present a longitudinal study on 22 healthy volunteers divided in two groups. The first was allowed to have normal oral hygiene and the second was subjected to an induced gingivitis for two weeks by cessation of oral hygiene. The spectral reflectance ratio at 615 and 460 nm, R(615)/R(460), was proposed as a method to quantify and map the erythema spatial distribution. These wavelengths represent spectral absorption crossovers observed between oxygenated and deoxygenated hemoglobin. The spectral method presented shows a significant separation (p<0.01) between the groups when gingivitis was induced and correlates significantly (p<0.05) with the clinical gingival index scores. We believe that these investigations could contribute to the development of functional imaging methods for periodontal disease detection and monitoring.
Christian M. Zakian, Iain A. Pretty, Roger Ellwood, David Hamlin, "In vivo quantification of gingival inflammation using spectral imaging," Journal of Biomedical Optics 13(5), 054045 (1 September 2008). http://dx.doi.org/10.1117/1.2982536





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