1 September 2008 Analysis of hollow-core photonic bandgap fibers for evanescent wave biosensing
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J. of Biomedical Optics, 13(5), 054048 (2008). doi:10.1117/1.2983676
Abstract
Hollow-core photonic bandgap fiber (HC-PBGF)–based evanescent wave biosensors are demonstrated and analyzed theoretically and experimentally. With 95% of the guided light power residing in the samples, the measured absorbance for a 30-cm-long fiber filled with a 0.2 μM Alexa Fluor 700–labeled DNA Oligo solution is 1.06. This is in good agreement with the theoretical prediction, which is evaluated by using the refractive index scaling law. The HC-PBGFs thus offer both efficiency and simplicity for the detection of biomolecules in ultra-small sample volumes.
Jian Sun, Chi-Chiu Chan, Yifan Zhang, Ping Shum, "Analysis of hollow-core photonic bandgap fibers for evanescent wave biosensing," Journal of Biomedical Optics 13(5), 054048 (1 September 2008). http://dx.doi.org/10.1117/1.2983676
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KEYWORDS
Optical fibers

Refractive index

Water

Biological research

Absorption

Biosensors

Waveguides

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