1 September 2008 Manipulation of mammalian cells using a single-fiber optical microbeam
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Abstract
The short working distance of microscope objectives has severely restricted the application of optical micromanipulation techniques at larger depths. We show the first use of fiber-optic tweezers toward controlled guidance of neuronal growth cones and stretching of neurons. Further, by mode locking, the fiber-optic tweezers beam was converted to fiber-optic scissors, enabling dissection of neuronal processes and thus allowing study of the subsequent response of neurons to localized injury. At high average powers, lysis of a three-dimensionally trapped cell was accomplished.
© (2008) Society of Photo-Optical Instrumentation Engineers (SPIE)
Samarendra Kumar Mohanty, Samarendra Kumar Mohanty, Khyati Mohanty, Khyati Mohanty, Michael W. Berns, Michael W. Berns, } "Manipulation of mammalian cells using a single-fiber optical microbeam," Journal of Biomedical Optics 13(5), 054049 (1 September 2008). https://doi.org/10.1117/1.2983663 . Submission:
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