1 November 2008 Quantitative depth analysis of optic nerve head using stereo retinal fundus image pair
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Abstract
Depth analysis of the optic nerve head (ONH) in the retinal fundus is important for the early detection of glaucoma. In this study, we investigate an automatic reconstruction method for the quantitative depth measurement of the ONH from a stereo retinal fundus image pair. We propose a technique to obtain the depth value from the stereo retinal fundus image pair, which mainly consists of five steps: 1. cutout of the ONH region from the stereo retinal fundus image pair, 2. registration of the stereo image pair, 3. disparity measurement, 4. noise reduction, and 5. quantitative depth calculation. Depth measurements of 12 normal eyes are performed using the stereo fundus camera and the Heidelberg Retina Tomograph (HRT), which is a confocal laser-scanning microscope. The depth values of the ONH obtained from the stereo retinal fundus image pair were in good accordance with the value obtained using HRT (r=0.80±0.15). These results indicate that our proposed method could be a useful and easy-to-handle tool for assessing the cup depth of the ONH in routine diagnosis as well as in glaucoma screening.
© (2008) Society of Photo-Optical Instrumentation Engineers (SPIE)
Toshiaki Nakagawa, Toshiaki Nakagawa, Takayoshi Suzuki, Takayoshi Suzuki, Yoshinori Hayashi, Yoshinori Hayashi, Yutaka Mizukusa, Yutaka Mizukusa, Yuji Hatanaka, Yuji Hatanaka, Kyoko Ishida, Kyoko Ishida, Takeshi Hara, Takeshi Hara, Hiroshi Fujita, Hiroshi Fujita, Tetsuya Yamamoto, Tetsuya Yamamoto, } "Quantitative depth analysis of optic nerve head using stereo retinal fundus image pair," Journal of Biomedical Optics 13(6), 064026 (1 November 2008). https://doi.org/10.1117/1.3041711 . Submission:
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