1 November 2008 Improving surface-enhanced Raman scattering effect using gold-coated hierarchical polystyrene bead substrates modified with postgrowth microwave treatment
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Abstract
We report a novel postgrowth microwave heating implementation by selectively modifying hierarchical polystyrene (PS) bead substrates coated with gold (Au) films to effectively improve the surface-enhanced Raman scattering (SERS) effect on the analytes. The SERS signal of probe molecule rhodamine 6G (Rh 6G) on the microwave-treated Au–PS substrates can be improved by 10-fold, while the detection limit of Rh 6G in concentration can be enhanced by two orders of magnitude compared to the as-growth substrates. The high-quality SERS spectrum of saliva can also be acquired using the modified substrates, demonstrating the potential for the realization of the high-performance SERS substrates for biomedical applications.
© (2008) Society of Photo-Optical Instrumentation Engineers (SPIE)
Clement Yuen, Clement Yuen, Wei Zheng, Wei Zheng, Zhiwei Huang, Zhiwei Huang, } "Improving surface-enhanced Raman scattering effect using gold-coated hierarchical polystyrene bead substrates modified with postgrowth microwave treatment," Journal of Biomedical Optics 13(6), 064040 (1 November 2008). https://doi.org/10.1117/1.3050447 . Submission:
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