1 May 2009 In vivo trans-rectal ultrasound-coupled optical tomography of a transmissible venereal tumor model in the canine pelvic canal
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J. of Biomedical Optics, 14(3), 030506 (2009). doi:10.1117/1.3149852
Abstract
In vivo trans-rectal near-infrared (NIR) optical tomography was performed concurrently with, albeit reconstructed without spatial a prior of, trans-rectal ultrasound (US) on transmissible venereal tumor (TVT) developed as a model in the canine pelvic canal. Studies were taken longitudinally at prior to, 14 days after, and 35 days after the TVT injection. As the tumor grew, the nodules became increasingly hyperabsorptive and moderately hyperscattering on NIR. The regions of strong NIR contrast, especially on absorption images, correlated well with those of US hypoechoic masses indicative of tumors. Combining the information of trans-rectal NIR and US detected the tumor more accurately than did the US alone at 14 days postinjection.
Zhen Jiang, G. Reed Holyoak, Kenneth Eugene Bartels, Jerry W. Ritchey, Guan Xu, Charles F. Bunting, Gennady Slobodov, Daqing Piao, "In vivo trans-rectal ultrasound-coupled optical tomography of a transmissible venereal tumor model in the canine pelvic canal," Journal of Biomedical Optics 14(3), 030506 (1 May 2009). http://dx.doi.org/10.1117/1.3149852
Submission: Received ; Accepted
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KEYWORDS
Near infrared

Tumors

Prostate

In vivo imaging

Optical tomography

Tissues

Absorption

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