1 September 2009 Doppler optical microangiography improves the quantification of local fluid flow and shear stress within 3-D porous constructs
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J. of Biomedical Optics, 14(5), 050504 (2009). doi:10.1117/1.3233590
Abstract
Traditional phase-resolved Doppler optical coherence tomography (DOCT) has been reported to have potential for characterizing local fluid flow within a microporous scaffold. In this work, we apply Doppler optical microangiography (DOMAG), a new imaging technique developed by combining optical microangiography (OMAG) with a phase-resolved method, for improved assessment of local fluid flow and its derived parameters, shear stress, and interconnectivity, within highly scattering porous constructs. Compared with DOCT, we demonstrate a dramatic improvement of DOMAG in quantifying flow-related properties within scaffolds in situ for functional tissue engineering.
Yali Jia, Lin An, Ruikang K. Wang, "Doppler optical microangiography improves the quantification of local fluid flow and shear stress within 3-D porous constructs," Journal of Biomedical Optics 14(5), 050504 (1 September 2009). http://dx.doi.org/10.1117/1.3233590
Submission: Received ; Accepted
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KEYWORDS
Microfluidics

Microfluidic imaging

Tissues

Tissue optics

Doppler tomography

Interference (communication)

Scattering

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