Remittance at a single wavelength of 390  nm to quantify epidermal melanin concentration

Willem Verkruysse; Lars Othar Svaasand; Walfre Franco; J. Stuart Nelson

doi:10.1117/1.3065542

1 January 2009 Remittance at a single wavelength of 390 nm to quantify epidermal melanin concentration

Willem Verkruysse; Lars Othar Svaasand; Walfre Franco; J. Stuart Nelson

Author Affiliations +

J. of Biomedical Optics, 14(1), 014005 (2009). https://doi.org/10.1117/1.3065542

Abstract

Objective quantification of epidermal melanin concentration (EMC) should be useful in laser dermatology to determine the individual maximum safe radiant exposure (IMSRE). We propose a single-wavelength remittance measurement at 390 nm as an alternative optical method to determine EMC and IMSRE. Remittance spectra (360 to 740 nm), melanin index (MI) measurements and the transient radiometric temperature increase,Δ T(t), upon skin irradiation with an Alexandrite laser (755 nm, 3-ms pulse duration, 6 J/cm²) were measured on 749 skin spots (arm and calf) on 23 volunteers (skin phototypes I to IV). Due to the shallow penetration depth and independence of blood oxygen saturation (isosbestic point), remittance at 390 nm appears to provide better estimates for EMC and IMSRE than MI.

Citation Download Citation

Willem Verkruysse, Willem Verkruysse, Lars Othar Svaasand, Lars Othar Svaasand, Walfre Franco, Walfre Franco, J. Stuart Nelson, J. Stuart Nelson, } "Remittance at a single wavelength of 390 nm to quantify epidermal melanin concentration," Journal of Biomedical Optics 14(1), 014005 (1 January 2009). https://doi.org/10.1117/1.3065542 . Submission:

ACCESS THE FULL ARTICLE

PERSONAL SIGN IN
Full access may be available with your subscription

Email or Username Forgot your username?

Password Forgot your password?

Show

Remember Email/Username on this computer

Remember Password

No SPIE account? Create an account
or Institutional Sign In via Shibboleth

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $20.00

Non-members: $25.00 ADD TO CART

Show All Keywords

Keywords/Phrases

Search In:

Publication Years