1 January 2010 Integrated intravascular optical coherence tomography ultrasound imaging system
Author Affiliations +
J. of Biomedical Optics, 15(1), 010512 (2010). doi:10.1117/1.3308642
We report on a dual-modality optical coherence tomography (OCT) ultrasound (US) system for intravascular imaging. To the best of our knowledge, we have developed the first integrated OCT-US probe that combines OCT optical components with an US transducer. The OCT optical components mainly consist of a single-mode fiber, a gradient index lens for light-beam focusing, and a right-angled prism for reflecting light into biological tissue. A 40-MHz piezoelectric transducer (PZT-5H) side-viewing US transducer was fabricated to obtain the US image. These components were integrated into a single probe, enabling both OCT and US imaging at the same time. In vitro OCT and ultrasound images of a rabbit aorta were obtained using this dual-modality imaging system. This study demonstrates the feasibility of an OCT-US system for intravascular imaging, which is expected to have a prominent impact on early detection and characterization of atherosclerosis.
Jiechen Yin, Hao-Chung Yang, Xiang Li, Jun Zhang, Qifa Zhou, Chang Hong Hu, K. Kirk Shung, Zhongping Chen, "Integrated intravascular optical coherence tomography ultrasound imaging system," Journal of Biomedical Optics 15(1), 010512 (1 January 2010). http://dx.doi.org/10.1117/1.3308642
Submission: Received ; Accepted

Optical coherence tomography

Imaging systems


Intravascular ultrasound


Optical components

Signal detection

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