1 March 2010 Static and dynamic light scattering of healthy and malaria-parasite invaded red blood cells
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J. of Biomedical Optics, 15(2), 020506 (2010). doi:10.1117/1.3369966
Abstract
We present the light scattering of individual Plasmodium falciparum-parasitized human red blood cells (Pf-RBCs), and demonstrate progressive alterations to the scattering signal arising from the development of malaria-inducing parasites. By selectively imaging the electric fields using quantitative phase microscopy and a Fourier transform light scattering technique, we calculate the light scattering maps of individual Pf-RBCs. We show that the onset and progression of pathological states of the Pf-RBCs can be clearly identified by the static scattering maps. Progressive changes to the biophysical properties of the Pf-RBC membrane are captured from dynamic light scattering.
YongKeun Park, Monica Diez-Silva, Dan Fu, Gabriel Popescu, Wonshik Choi, Ishan Barman, Subra Suresh, Michael S. Feld, "Static and dynamic light scattering of healthy and malaria-parasite invaded red blood cells," Journal of Biomedical Optics 15(2), 020506 (1 March 2010). http://dx.doi.org/10.1117/1.3369966
Submission: Received ; Accepted
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KEYWORDS
Light scattering

Scattering

Dynamic light scattering

Blood

Laser scattering

Optical testing

Fourier transforms

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