1 May 2010 Real-time monitoring of cardiac radio-frequency ablation lesion formation using an optical coherence tomography forward-imaging catheter
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J. of Biomedical Optics, 15(3), 030516 (2010). doi:10.1117/1.3459134
Abstract
Radio-frequency ablation (rfa) is the standard of care for the treatment of cardiac arrhythmias; however, there are no direct measures of the successful delivery of ablation lesions. Optical coherence tomography (OCT) imaging has the potential to provide real-time monitoring of cardiac rfa therapy, visualizing lesion formation and assessing tissue contact in the presence of blood. A rfa-compatible forward-imaging conical scanning probe is prototyped to meet this need. The forward-imaging probe provides circular scanning, with a 2-mm scan diameter and 30-µm spot size. During the application of rf energy, dynamics are recorded at 20 frames per second with a 40-kHz A-line rate. Real-time monitoring of cardiac rfa lesion formation and imaging in the presence of blood is demonstrated ex vivo in a swine left ventricle with a forward, flexible, circular scanning OCT catheter.
Christine P. Fleming, Hui Wang, Kara J. Quan, Andrew M. Rollins, "Real-time monitoring of cardiac radio-frequency ablation lesion formation using an optical coherence tomography forward-imaging catheter," Journal of Biomedical Optics 15(3), 030516 (1 May 2010). http://dx.doi.org/10.1117/1.3459134
Submission: Received ; Accepted
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KEYWORDS
Optical coherence tomography

Radiofrequency ablation

Blood

Tissues

Visualization

Tissue optics

Prototyping

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