1 July 2010 Combined photoacoustic and oblique-incidence diffuse reflectance system for quantitative photoacoustic imaging in turbid media
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J. of Biomedical Optics, 15(4), 046016 (2010). doi:10.1117/1.3470336
Abstract
While photoacoustic imaging is capable of producing high-resolution biomedical images with optical absorption contrast, optical property quantification has thus far remained challenging. One reason for this is that laser-induced photoacoustic signal amplitudes are proportional to not only the local optical absorption coefficient, but also the local laser fluence in the tissue. Unfortunately, local laser fluence is often unknown, but could possibly be estimated if local bulk tissue optical properties were known. One method to estimate tissue optical properties is a technique known as oblique incidence diffuse reflectance (OIR). We report on an integrated OIR and photoacoustic imaging system and demonstrate, using phantom experiments, improved ability to quantitatively estimate optical properties of a turbid medium.
Janaka C. Ranasinghesagara, Roger J. Zemp, "Combined photoacoustic and oblique-incidence diffuse reflectance system for quantitative photoacoustic imaging in turbid media," Journal of Biomedical Optics 15(4), 046016 (1 July 2010). http://dx.doi.org/10.1117/1.3470336
Submission: Received ; Accepted
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KEYWORDS
Photoacoustic spectroscopy

Absorption

Optical properties

Diffuse reflectance spectroscopy

Photoacoustic imaging

Transducers

Ultrasonography

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