1 July 2010 Parametric imaging of cancer with optical coherence tomography
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J. of Biomedical Optics, 15(4), 046029 (2010). doi:10.1117/1.3479931
Abstract
We present a parametric optical coherence tomography (OCT) technique to improve contrast between malignant and healthy non-neoplastic tissue. The technique incorporates a fully automated method to extract tissue attenuation characteristics. Results are represented visually as a parametric en face image, where the parameter used for contrast is indicative of the relative optical attenuation coefficient of the tissue. We present the first parametric OCT images of human lymph nodes containing malignant cells, and demonstrate improved tissue contrast over en face OCT images.
Robert A. McLaughlin, Loretta Scolaro, Peter Robbins, Christobel Saunders, Steven L. Jacques, David D. Sampson, "Parametric imaging of cancer with optical coherence tomography," Journal of Biomedical Optics 15(4), 046029 (1 July 2010). http://dx.doi.org/10.1117/1.3479931
Submission: Received ; Accepted
JOURNAL ARTICLE
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KEYWORDS
Optical coherence tomography

Tissues

Lymphatic system

Signal attenuation

Tissue optics

Glasses

Cancer

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