1 September 2010 Three-dimensional optical imaging of microvascular networks within intact lymph node in vivo
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J. of Biomedical Optics, 15(5), 050501 (2010). doi:10.1117/1.3496301
Abstract
Sentinel lymph nodes (SLNs) are the first lymph nodes to drain wastes originated from cancerous tissue. There is a need for an in vivo imaging method that can image the intact SLN to further our understanding of its normal as well as abnormal functions. We report the use of ultrahigh sensitive optical microangiography (UHS-OMAG) to image functional microvascular and lymphatic vessel networks that innervate the intact lymph node in mice in vivo. The promising results show a potential role of UHS-OMAG in the future understanding and diagnosis of the SLN involvement in cancer development.
Yeongri Jung, Zhongwei Zhi, Ruikang K. Wang, "Three-dimensional optical imaging of microvascular networks within intact lymph node in vivo," Journal of Biomedical Optics 15(5), 050501 (1 September 2010). http://dx.doi.org/10.1117/1.3496301
Submission: Received ; Accepted
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KEYWORDS
Lymphatic system

Tissues

In vivo imaging

3D image processing

Blood vessels

Optical coherence tomography

Visualization

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