Open Access
1 January 2010 Laser speckle contrast imaging in biomedical optics
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Abstract
First introduced in the 1980s, laser speckle contrast imaging is a powerful tool for full-field imaging of blood flow. Recently laser speckle contrast imaging has gained increased attention, in part due to its rapid adoption for blood flow studies in the brain. We review the underlying physics of speckle contrast imaging and discuss recent developments to improve the quantitative accuracy of blood flow measures. We also review applications of laser speckle contrast imaging in neuroscience, dermatology and ophthalmology.
©(2010) Society of Photo-Optical Instrumentation Engineers (SPIE)
David A. Boas and Andrew K. Dunn "Laser speckle contrast imaging in biomedical optics," Journal of Biomedical Optics 15(1), 011109 (1 January 2010). https://doi.org/10.1117/1.3285504
Published: 1 January 2010
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Cited by 903 scholarly publications and 30 patents.
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KEYWORDS
Speckle

Blood circulation

Laser speckle contrast imaging

Scattering

Brain

Speckle pattern

Statistical analysis

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