1 March 2010 Saturation effect in functional photoacoustic imaging
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We investigate the saturation effect, which describes the violation of the linearity between the measured photoacoustic amplitude and the object's optical absorption coefficient in functional photoacoustic imaging when the optical absorption in the object increases. We model the optical energy deposition and photoacoustic signal generation and detection in a semi-infinite optical absorbing object. Experiments are carried out by measuring photoacoustic signals generated from an ink-filled plastic tube. The saturation effect is studied by varying the optical absorption coefficient in the model and the ink concentration in the photoacoustic experiments. By changing the center frequency of the ultrasonic detector, the requirement to minimize the saturation effect in functional photoacoustic imaging is established.
© (2010) Society of Photo-Optical Instrumentation Engineers (SPIE)
Jing Wang, Jing Wang, Tan Liu, Tan Liu, Shuliang Jiao, Shuliang Jiao, Ruimin Chen, Ruimin Chen, Qifa Zhou, Qifa Zhou, K. Kirk Shung, K. Kirk Shung, Lihong V. Wang, Lihong V. Wang, Hao F. Zhang, Hao F. Zhang, } "Saturation effect in functional photoacoustic imaging," Journal of Biomedical Optics 15(2), 021317 (1 March 2010). https://doi.org/10.1117/1.3333549 . Submission:

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