1 May 2010 Near-infrared imaging of the sinuses: preliminary evaluation of a new technology for diagnosing maxillary sinusitis
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J. of Biomedical Optics, 15(3), 036011 (2010). doi:10.1117/1.3431718
Diagnosing sinusitis remains a challenge for primary care physicians. There is a need for a simple, office-based technique to aid in the diagnosis of sinusitis without the cost and radiation risk of conventional radiologic imaging. We designed a low-cost near-infrared (NIR) device to transilluminate the maxillary sinuses. The use of NIR light allows for greater interrogation of deep-tissue structures as compared to visible light. NIR imaging of 21 patients was performed and compared with computed tomography (CT) scans. Individual maxillary sinuses were scored on a scale from 0 to 2 based on their degree of aeration present on CT and similarly based on the NIR signal penetration into the maxilla on NIR images. Our results showed that air-filled and fluid/tissue-filled spaces can be reasonably distinguished by their differing NIR signal penetration patterns, with average NIR imaging scores for fluid-filled maxillary sinuses (0.93±0.78, n=29) significantly lower than those for normal maxillary sinuses (1.62±0.57, n=13) (p=0.003). NIR imaging of the sinuses is a simple, safe, and cost-effective modality that can potentially aid in the diagnosis of sinusitis. Long-term, significant device refinement and large clinical trials will be needed to determine the diagnostic accuracy of this technique.
Usama Mahmood, Albert E. Cerussi, Reza Dehdari, Quoc Nguyen, Timothy Kelley, Bruce Jason Tromberg, Brian Jet-Fei Wong, "Near-infrared imaging of the sinuses: preliminary evaluation of a new technology for diagnosing maxillary sinusitis," Journal of Biomedical Optics 15(3), 036011 (1 May 2010). https://doi.org/10.1117/1.3431718

Near infrared

Computed tomography

Imaging systems

Light sources

New and emerging technologies



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