Needle-compatible single fiber bundle image guide reflectance endoscope

Jiantang Sun; Chenghao Shu; Benjamin Appiah; Rebekah A. Drezek

doi:10.1117/1.3465558

1 July 2010 Needle-compatible single fiber bundle image guide reflectance endoscope

Jiantang Sun, Chenghao Shu, Benjamin Appiah, Rebekah A. Drezek

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Journal of Biomedical Optics, Vol. 15, Issue 4, 040502 (July 2010). https://doi.org/10.1117/1.3465558

Abstract

We developed a miniaturized high-resolution low-cost reflectance-mode fiber microscope (RFM) aimed at optical tissue biopsy applications using a polarized imaging configuration to suppress background noise from specular reflectance. The RFM is equipped with an air-cooled light-emitting-diode illumination module and a single 450-µm outer-diameter fiber bundle image guide compatible with a 20-gauge needle. The dual illumination and image acquisition nature of the fiber bundle simplifies the system and reduces the total cost. Imaging tests with a United States Air Force resolution target demonstrate a lateral resolution of ~3.5 µm. The performance of the imaging system is evaluated by examining samples of cells and excised human tissue. Still and video rate images are obtainable in reflectance mode using intrinsic contrast.

©(2010) Society of Photo-Optical Instrumentation Engineers (SPIE)

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Jiantang Sun, Chenghao Shu, Benjamin Appiah, and Rebekah A. Drezek "Needle-compatible single fiber bundle image guide reflectance endoscope," Journal of Biomedical Optics 15(4), 040502 (1 July 2010). https://doi.org/10.1117/1.3465558

Published: 1 July 2010

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