Open Access
1 November 2010 Spectroscopic visualization of nanoscale deformation in bone: interaction of light with partially disordered nanostructure
Zhengbin Xu, Xuanhao Sun, Jingjing Liu, Qinghai Song, Matthew Muckley, Ozan Akkus, Young L. Kim
Author Affiliations +
Abstract
Given that bone is an intriguing nanostructured dielectric as a partially disordered complex structure, we apply an elastic light scattering-based approach to image prefailure deformation and damage of bovine cortical bone under mechanical testing. We demonstrate that our imaging method can capture nanoscale deformation in a relatively large area. The unique structure, the high anisotropic property of bone, and the system configuration further allow us to use the transfer matrix method to study possible spectroscopic manifestations of prefailure deformation. Our sensitive yet simple imaging method could potentially be used to detect nanoscale structural and mechanical alterations of hard tissue and biomaterials in a fairly large field of view.
©(2010) Society of Photo-Optical Instrumentation Engineers (SPIE)
Zhengbin Xu, Xuanhao Sun, Jingjing Liu, Qinghai Song, Matthew Muckley, Ozan Akkus, and Young L. Kim "Spectroscopic visualization of nanoscale deformation in bone: interaction of light with partially disordered nanostructure," Journal of Biomedical Optics 15(6), 060503 (1 November 2010). https://doi.org/10.1117/1.3514633
Published: 1 November 2010
Lens.org Logo
CITATIONS
Cited by 17 scholarly publications.
Advertisement
Advertisement
RIGHTS & PERMISSIONS
Get copyright permission  Get copyright permission on Copyright Marketplace
KEYWORDS
Bone

Collagen

Spectroscopy

Imaging spectroscopy

Nanostructures

Refractive index

Visualization

Back to Top