Angular domain transillumination imaging optimization with an ultrafast gated camera

Fartash Vasefi; Mohamadreza Najiminaini; Eldon Ng; Bozena Kaminska; Glenn H. Chapman; Jeffrey J. L. Carson

doi:10.1117/1.3505020

1 November 2010 Angular domain transillumination imaging optimization with an ultrafast gated camera

Fartash Vasefi, Mohamadreza Najiminaini, Eldon Ng, Bozena Kaminska, Glenn H. Chapman, Jeffrey J. L. Carson

Author Affiliations +

Journal of Biomedical Optics, Vol. 15, Issue 6, 061710 (November 2010). https://doi.org/10.1117/1.3505020

Abstract

By employing high-aspect-ratio parallel microchannels as an angular filter, quasiballistic photons sensitive to internal structures in a turbid medium can be captured. Scattered photons exiting the turbid medium typically exhibit trajectories with random angles compared to the initial trajectory and are mostly rejected by the filter. However, angular filter arrays cannot differentiate between quasiballistic photons (early arriving) and photons that happen to attain a scattered trajectory that is within the acceptance angle (late arriving). Therefore, we have two objectives: (1) to experimentally characterize the angular distribution and proportion of minimally deviated quasiballistic photons and multiply scattered photons in a turbid medium and (2) to combine time and angular gating principles so that early and late arriving photons can be distinguished. From the angular distribution data, the angular filter with angular acceptance about 0.4 deg yields the highest image contrast for transillumination images. The use of angular domain imaging(ADI) with time-gating enables visualization of submillimeter absorbing objects with approximately seven times higher image contrast compared to ADI in a turbid medium with a scattering level of six times the reduced mean free path.

©(2010) Society of Photo-Optical Instrumentation Engineers (SPIE)

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Fartash Vasefi, Mohamadreza Najiminaini, Eldon Ng, Bozena Kaminska, Glenn H. Chapman, and Jeffrey J. L. Carson "Angular domain transillumination imaging optimization with an ultrafast gated camera," Journal of Biomedical Optics 15(6), 061710 (1 November 2010). https://doi.org/10.1117/1.3505020

Published: 1 November 2010

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KEYWORDS

Photons

Scattering

Light scattering

Cameras

Imaging systems

Chromium

Sensors

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