1 March 2011 Closure of skin incisions by laser-welding with a combination of two near-infrared diode lasers: preliminary study for determination of optimal parameters
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J. of Biomedical Optics, 16(3), 038001 (2011). doi:10.1117/1.3552648
Abstract
Laser welding has the potential to become an effective method for wound closure and healing without sutures. Closure of skin incisions by laser welding with a combination of two near-infrared lasers (980 and 1064 nm), was performed for the first time in this study. One centimeter long, full-thickness incisions were made on the Wistar rat's dorsal skin. The efficiencies of laser-welding with different parameters were investigated. Incision-healing, histology examination, and a tensile strength test of incisions were recorded. Laser welding with the irradiance level of 15.9 W/cm2 for both 980 and 1064-nm lasers and exposure time of 5 s per spot in continuous wave mode yielded a more effective closure and healing with minimal thermal damage, faster recovery, and stronger apposition in comparison with a suturing technique. The conclusion is that skin welding with a combination of two near-infrared diode lasers can be a good candidate for incision closure, and further investigations are in progress for clinical use.
Liming Hu, Biao Wang, Junsheng Cao, Zhenhua Tian, Zhijian Gao, Li Qin, Yun Liu, Lijun Wang, Zhihua Lu, Xiaobo Ma, Xiaodong Wu, "Closure of skin incisions by laser-welding with a combination of two near-infrared diode lasers: preliminary study for determination of optimal parameters," Journal of Biomedical Optics 16(3), 038001 (1 March 2011). http://dx.doi.org/10.1117/1.3552648
Submission: Received ; Accepted
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KEYWORDS
Laser welding

Skin

Semiconductor lasers

Laser tissue interaction

Tissues

Laser applications

Wound healing

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