1 April 2011 Contact and contactless diffuse reflectance spectroscopy: potential for recovery monitoring of vascular lesions after intense pulsed light treatment
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J. of Biomedical Optics, 16(4), 040505 (2011). doi:10.1117/1.3569119
Abstract
Optical fiber contact probe diffuse reflectance spectroscopy and remote multispectral imaging methods in the spectral range of 400 to 1100 nm were used for skin vascular malformation assessment and recovery tracing after treatment by intense pulsed light. The results confirmed that oxy-hemoglobin relative changes and the optical density difference between lesion and healthy skin in the spectral region 500 to 600 nm may be successfully used for objective appraisal of the therapy effect. Color redness parameter a* = 2 is suggested as a diagnostic border to distinguish healthy skin and vascular lesions, and as the indicator of phototreatment efficiency. Valuable diagnostic information on large area (>5 mm) lesions and lesions with uncertain borders can be proved by the multispectral imaging method.
Ilona Kuzmina, Ilze Diebele, Janis Spigulis, Lauma Valeine, Anna Berzina, Anita Abelite, "Contact and contactless diffuse reflectance spectroscopy: potential for recovery monitoring of vascular lesions after intense pulsed light treatment," Journal of Biomedical Optics 16(4), 040505 (1 April 2011). http://dx.doi.org/10.1117/1.3569119
Submission: Received ; Accepted
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KEYWORDS
Skin

Multispectral imaging

Diffuse reflectance spectroscopy

Absorption

Diagnostics

Absorbance

Near infrared

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