1 May 2011 Fiber loop ringdown DNA and bacteria sensors
Author Affiliations +
J. of Biomedical Optics, 16(5), 050501 (2011). doi:10.1117/1.3572046
Abstract
We report a new type of refractive index-based biosensor using a fiber loop ringdown evanescent field (FLRD-EF) sensing scheme, in which the sensing signal is a time constant and detection sensitivity is enhanced by the multipass nature of the ringdown technique. Bulk index-based detections of three different single strand DNAs and one type of bacteria are demonstrated for the FLRD-EF sensors that utilize a partially-etched single mode fiber as the sensor head. Stepwise coating of the sensor head with poly-L-lysine and a probe DNA has enabled surface index-based label-free target DNA sensing. We expect an array of FLRD-EF biosensors to be created, which are superior to counterparts in terms of simplicity, low cost, and high sensitivity.
Chamini Herath, Chuji Wang, Malik Kaya, David Chevalier, "Fiber loop ringdown DNA and bacteria sensors," Journal of Biomedical Optics 16(5), 050501 (1 May 2011). http://dx.doi.org/10.1117/1.3572046
Submission: Received ; Accepted
JOURNAL ARTICLE
4 PAGES


SHARE
KEYWORDS
Sensors

Head

Bacteria

Coating

Single mode fibers

Biosensors

Water

RELATED CONTENT

An-optical-fiber-humidity-sensor-based-on-optical-absorption
Proceedings of SPIE (November 29 2011)
Thin-silica-diaphragm-based-fiber-optic-acoustic-sensors
Proceedings of SPIE (December 08 1999)
Evanescent-Wave-Fiber-Optic-Chemical-Sensor
Proceedings of SPIE (October 14 1987)

Back to Top