Emil N. Sobol,Olga I. Baum Institute on Laser and Information Technologies (Russian Federation) Anatoliy B. Shekhter,Anna Guller I.M. Sechenov Moscow Medical Academy (Russian Federation) Andrey V. Baskov Medical Ctr. for Vertebrology and Orthopedics (Russian Federation)
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Laser radiation provides a means to control the fields of temperature and thermo mechanical stress, mass transfer, and modification of fine structure of the cartilage matrix. The aim of this outlook paper is to review physical and biological aspects of laser-induced regeneration of cartilage and to discuss the possibilities and prospects of its clinical applications. The problems and the pathways of tissue regeneration, the types and features of cartilage will be introduced first. Then we will review various actual and prospective approaches for cartilage repair; consider possible mechanisms of laser-induced regeneration. Finally, we present the results in laser regeneration of joints and spine disks cartilages and discuss some future applications of lasers in regenerative medicine.