In vivo two-photon microscopy to 1.6-mm depth in mouse cortex

Demirhan Kobat; Nicholas G. Horton; Chris Xu

doi:10.1117/1.3646209

1 October 2011 In vivo two-photon microscopy to 1.6-mm depth in mouse cortex

Demirhan Kobat, Nicholas G. Horton, Chris Xu

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Journal of Biomedical Optics, Vol. 16, Issue 10, 106014 (October 2011). https://doi.org/10.1117/1.3646209

Abstract

Deep tissue in vivo two-photon fluorescence imaging of cortical vasculature in a mouse brain using 1280-nm excitation is presented. A record imaging depth of 1.6 mm in mouse cortex is achieved in vivo, approximately reaching the fundamental depth limit in scattering tissue.

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Demirhan Kobat, Nicholas G. Horton, and Chris Xu "In vivo two-photon microscopy to 1.6-mm depth in mouse cortex," Journal of Biomedical Optics 16(10), 106014 (1 October 2011). https://doi.org/10.1117/1.3646209

Published: 1 October 2011

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